<p><b>Safer With Less Warfarin</b></p> <ul> <li style="font-weight: 400"><span style="font-weight: 400">The only aortic mechanical heart valve FDA and CE approved with less warfarin</span></li> <li style="font-weight: 400"><span style="font-weight: 400">>60% reduction in bleeding</span><span style="font-weight: 400">2</span></li> <li style="font-weight: 400"><span style="font-weight: 400">No increase in thromboembolism (TE)</span></li> </ul> <p><span style="font-weight: 400">The On-X Aortic Valve is a newer generation heart valve made of a unique material and design characteristics compared with earlier generations of mechanical heart valves. The On-X Aortic Valve is the only mechanical valve with FDA and CE approval to be used safely with less blood thinner (warfarin).The AHA and ACC guidelines state that less blood thinner may be reasonable for patients with the mechanical On-X Aortic Valve.</span><span style="font-weight: 400">3</span><span style="font-weight: 400"> In a prospective randomized clinical trial, On-X Aortic Valve patients with a reduced blood thinner dose</span><span style="font-weight: 400">* </span><span style="font-weight: 400">had > 60% fewer bleeding events without an increase in risk of stroke.</span><span style="font-weight: 400">2 </span><span style="font-weight: 400"> The On-X Aortic Valve, as a mechanical heart valve, has a much lower risk of reoperation than tissue (bioprosthetic) valves, with the additional benefit of less bleeding risk than other mechanical aortic valves because of the significantly lower amount of blood thinner required.</span><span style="font-weight: 400">2,*</span></p> <p><span style="font-weight: 400">If you are under the age of 70 years old and need aortic valve replacement, ask your doctor about the On-X Aortic Valve, the only mechanical valve that is both designed  to last a lifetime and safer with less blood thinner.</span></p>